ICLM: Discover, teach, treatI.C. Learning & Memory

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Michele A Basso

The work performed in the Basso laboratory is aimed at unravelling the neuronal circuits of decision-making in health and disease. Her work spans multiple species and employs multiple technologies designed to understand how memory and sensory information are combined to give rise to our decisions.

Recent Publications:

Grimaldi, P., Hah Cho, S., Lau, H., and Basso, M.A. (2018). Superior Colliculus Neurons Signal Decision Rather Than Confidence: Analysis of Single Neurons. Journal of Neurophysiology 120: 2614-2629.

Perugini, A., Ditterich, J., Shaikh, AG., Knowlton, B., Basso, M.A. (2018). Paradoxical Decision Making: A Framework for Understanding Cognition in Parkinson’s Disease. Trends In Neurosciences 41(8):512-525.

Villalobos, C.,Wu, Q, Lee, P., May, PJ., and Basso, M.A. (2018). Parvalbumin (PV) and GABA microcircuits in the superior colliculus. Frontiers in Neural Circuits 12(35) https://doi.org/10.3389/fncir.2018.00035.

Odegaard, B., Grimaldi, P., Hah Cho, S., Peters, M.A., Lau, H., Basso, M.A. (2018). Superior colliculus neuronal ensemble activity reflects decisions rather than subjective confidence. Proceedings of the National Academy of Sciences 115(7):E1588-E1597.

Crapse, T., Lau, H. and Basso, M.A. (2018). A role for the superior colliculus in decision criteria. Neuron. 97(1):181-194.

Perugini, A.P. and Basso, M.A. (2017). Memory-based decision-making is independent of dopaminergic tone. Journal of Neurophysiology 119(3):849-86.

Basso, M.A. and May, P.J. (2017). Circuits for action and cognition: A view from the superior colliculus. Annual Review of Vision Science. 3:197-226.

Perugini, A., Ditterich, J and Basso, M.A. (2016) Patients with Parkinson’s disease show impaired use of priors in conditions of sensory uncertainty. Current Biology 26(14):1902-1910.